Transport in animals — IGCSE Science - Combined (0653) questions by topic

Labelling heart structures, identifying blood components from a photomicrograph, and explaining how vessel structure suits function are the recurring demands: naming an atrium on a heart diagram, distinguishing red blood cells from white cells, and linking artery wall thickness to blood pressure. Explain, describe and identify lead the command words, with explain specifically requiring a reason rather than a repeated observation.

The 17 real questions in this set, taken from 2023 to 2025 papers, carry 1 to 11 marks, so a single label can sit next to a full explanation of coronary heart disease risk. Practising under instant marking is useful for checking that an explanation links reduced blood flow to reduced oxygen delivery, rather than mentioning only one half of that chain.

What examiners look for

May–June 2025, Paper 23

Question 11 · 1 mark

The diagrams show cross-sections of two different blood vessels. Vessel P is shown as a circular cross-section with a relatively thick wall and a small central lumen. Vessel Q is…

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May–June 2025, Paper 31

Question 2 · 9 marks

Fig. 2.1 shows the structure of a human heart. The arrows in Fig. 2.1 show the direction of blood flow through the heart. Use letters P-S to complete the sentences about the heart…

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May–June 2025, Paper 33

Question 2 · 10 marks

A student investigates the effect of different physical activity on heart rate. Fig. 2.1 is a bar chart of the results, showing heart rate in beats per minute for five types of…

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May–June 2025, Paper 43

Question 1 · 9 marks

Fig. 1.1 is a photomicrograph of human blood. Three components are labelled: X (a small biconcave-looking cell with no nucleus, very numerous), Z (a larger cell with a prominent…

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May–June 2024, Paper 31

Question 7 · 8 marks

Fig. 7.1 shows part of the human circulatory system (lungs, heart and blood vessel R), with arrows showing the direction of blood flow. Identify the blood vessel labelled R in…

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May–June 2024, Paper 33

Question 1 · 9 marks

Fig. 1.1 is a diagram of the human heart, with labels for blood to the body, blood from the lungs, left atrium, left ventricle, and two gaps. Complete the labels on Fig. 1.1 (the…

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May–June 2024, Paper 41

Question 1 · 9 marks

Fig. 1.1 shows the structure of the human heart, with parts labelled X, Y, Z, and arrows showing the direction of blood flow (blood without oxygen leaves the heart, blood with…

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May–June 2024, Paper 42

Question 7 · 9 marks

Fig. 7.1 shows the double circulatory system in humans, with the lungs, the rest of the body, and blood vessels X and Y labelled; arrows show the direction of blood flow. Identify…

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October–November 2024, Paper 31

Question 4 · 11 marks

Anaemia is caused by a deficiency of iron in the diet. (a) Fig. 4.1 shows diagrams of the blood of a person without anaemia and the blood of a person with anaemia. Both show white…

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October–November 2024, Paper 32

Question 4 · 9 marks

(a) Fig. 4.1 is a diagram of the circulatory system in humans where the arrows show the direction of blood flow. Structure X (the septum) and structure Y (the pulmonary artery)…

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October–November 2024, Paper 33

Question 4 · 9 marks

(a) Fig. 4.1 is a diagram of the circulatory system in humans where the arrows show the direction of blood flow. Structure X (the septum) and structure Y (the pulmonary artery)…

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October–November 2024, Paper 42

Question 4 · 9 marks

(a) Fig. 4.1 shows drawings of three different blood vessels, W (thick-walled, medium lumen = artery), X (thin-walled, very small lumen = capillary), and Y (thick wall, large…

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October–November 2024, Paper 43

Question 7 · 10 marks

(a) Fig. 7.1 shows a diagram of the double circulatory system in humans (with lungs at the top, the heart in the middle, and the rest of the body at the bottom; the arrows show…

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May–June 2023, Paper 32

Question 1 · 9 marks

Fig. 1.1 is a diagram of a human heart with labels A, B, C, D and E pointing to different parts. State the letter in Fig. 1.1 that identifies the: right atrium septum

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May–June 2023, Paper 41

Question 1 · 10 marks

Fig. 1.1 shows the circulatory system of frogs and the circulatory system of humans (NOT TO SCALE), with a blood vessel labelled X in the human system. Identify the type of blood…

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May–June 2023, Paper 43

Question 7 · 8 marks

Fig. 7.1 shows the structure of the human heart (septum labelled). Draw a label line and the letter X on Fig. 7.1 to show one atrium.

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October–November 2023, Paper 42

Question 7 · 6 marks

Explain one way the structure of an artery is adapted to its function.

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