Gas exchange in humans — IGCSE Science - Combined (0653) questions by topic

Labelling the breathing system, reading breathing-rate graphs and explaining why breathing rate rises during exercise are the recurring demands here, alongside naming the diffusion process that moves oxygen into red blood cells at the alveolar surface. State, identify and describe lead the command words, each wanting a precise structure or process named rather than its general importance.

Only 8 real questions currently sit in this set, spanning 2023 to 2025 papers, worth 1 to 10 marks apiece, so every mark matters more than in larger topics. Submitting answers for instant marking is especially useful here for catching a mislabelled structure, such as confusing goblet cells with cilia, before it recurs across several questions.

What examiners look for

May–June 2025, Paper 22

Question 11 · 1 mark

The graphs show how the rate and depth of breathing varies when a student does four different activities. Which graph shows when the student is most active? Each graph (A-D) plots…

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May–June 2025, Paper 43

Question 3 · 8 marks

Fig. 3.1 shows part of the breathing system in humans. It shows a branching airway leading to clusters of small rounded sacs. One of the small tubes leading to a cluster of sacs…

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May–June 2023, Paper 31

Question 4 · 9 marks

Fig. 4.1 shows a model of the human gas exchange system. Draw a label line and the letter D to identify the diaphragm on Fig. 4.1.

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May–June 2023, Paper 42

Question 7 · 6 marks

Fig. 7.1 shows the gas exchange surface in humans (capillary wall, wall of alveolus, red blood cells, direction of oxygen movement). State the name of the process by which oxygen…

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October–November 2023, Paper 32

Question 1 · 10 marks

Fig. 1.1 is a diagram of the human gas exchange system, with parts labelled A, B, C, D, E. State the letter in Fig. 1.1 that identifies: one of the bronchi; the trachea.

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October–November 2023, Paper 33

Question 1 · 10 marks

Fig. 1.1 is a diagram of the human gas exchange system, with parts labelled A, B, C, D, E. State the letter in Fig. 1.1 that identifies: one of the bronchi; the trachea.

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October–November 2023, Paper 41

Question 4 · 7 marks

Fig. 4.1 shows part of the breathing system in humans, with part X above a labelled rib. State the name of the part labelled X in Fig. 4.1.

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October–November 2023, Paper 43

Question 1 · 10 marks

Fig. 1.1 shows part of the breathing system in humans, with the trachea labelled and parts A and B also marked. State the names of the parts labelled A and B in Fig. 1.1. A = ...…

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