Gas exchange in humans — IGCSE Biology (0610) questions by topic

Gas exchange in humans questions identify the thin walls and large surface area shared by gas exchange surfaces, judge the surface area, thickness and blood supply needed for skin-based gas exchange in some animals, name labelled parts of the human gas exchange system, and choose which intercostal muscles contract during breathing in.

Identify, state, explain, describe and complete lead 39 real questions worth 1 to 20 marks from 2023 to 2025 papers. Because inspiration and expiration involve intercostal muscles doing opposite things, submitting a chosen answer for instant marking flags immediately if the contraction and relaxation have been assigned to the wrong muscle group.

May–June 2025, Paper 11

Question 20 · 1 mark

Which statements describe the difference between the composition of inspired air and expired air? 1 The percentage of carbon dioxide in inspired air is greater than in expired…

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May–June 2025, Paper 12

Question 20 · 1 mark

Which substance can be used to test for carbon dioxide? A DCPIP B ethanol C iodine solution D limewater

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May–June 2025, Paper 13

Question 18 · 1 mark

The diagram shows part of the gas exchange system in humans. The diagram of the thorax shows labels T, U, V and W. W points to the cluster of air sacs (alveoli) at the end of the…

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May–June 2025, Paper 21

Question 18 · 1 mark

The graph shows how the volume of air in lungs changes when a person is breathing at rest. The trace is a regular wave of volume of air in lungs (y-axis) against time (x-axis);…

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May–June 2025, Paper 22

Question 20 · 1 mark

The table shows the breathing rate and the average total volume of air breathed by a student when exercising for 20 minutes. time / minutes breathing rate / breaths per minute…

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May–June 2025, Paper 23

Question 18 · 1 mark

The plotted points, 1 and 2, on the graph show two different types of structure in the breathing system of a human. [Graph: y-axis is "relative diameter of lumen", x-axis is…

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May–June 2025, Paper 32

Question 5 · 12 marks

Fig. 5.1 is a diagram of some of the muscles and bones found in the human gas exchange system. The diagram shows the rib cage with the sternum in the centre, a dome-shaped…

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May–June 2025, Paper 42

Question 1 · 20 marks

Fig. 1.1 shows part of the human gas exchange system. The diagram shows the trachea (with rings of cartilage labelled) dividing into branches that enter the lung. Structure A is…

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May–June 2025, Paper 43

Question 2 · 10 marks

Alveoli are the gas exchange surface in humans. State three features of alveoli that make them an effective gas exchange surface.

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October–November 2024, Paper 12

Question 25 · 1 mark

Which row matches a gas in expired air with a substance that can be used to test for the presence of that gas? (columns: gas present in expired air; test substance) A carbon…

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October–November 2024, Paper 13

Question 23 · 1 mark

Which structure connects directly to the alveoli? A bronchus B bronchiole C larynx D trachea

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October–November 2024, Paper 21

Question 22 · 1 mark

The intercostal muscles and diaphragm contract and relax during ventilation. Which row shows the actions of muscles that result in the largest volume inside the thorax? (columns:…

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October–November 2024, Paper 22

Question 21 · 1 mark

What causes air to enter the lungs? (columns: external intercostal muscles; volume of thorax; air pressure in thorax) A contract; decreases; decreases B relax; decreases;…

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October–November 2024, Paper 23

Question 17 · 1 mark

Muscles are responsible for the ventilation of the lungs during breathing. Which row describes their action during the inspiration of air? (columns: diaphragm muscles; external…

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October–November 2024, Paper 31

Question 5 · 12 marks

Fig. 5.1 shows part of the human gas exchange system, with a structure labelled F (in the upper airway) and an enlarged view of an alveolus and structure labelled G. Identify the…

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October–November 2024, Paper 32

Question 8 · 7 marks

Alveoli are the gas exchange surfaces in humans. State two features of gas exchange surfaces in humans.

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October–November 2024, Paper 42

Question 2 · 15 marks

Fig. 2.1 is a diagram of the gas exchange system in humans, showing the trachea and lungs with structures labelled X, Y and Z. State the names of the parts labelled X, Y and Z in…

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May–June 2023, Paper 11

Question 22 · 1 mark

What is the pathway of expired air as it travels out of the body? A alveoli → trachea → bronchiole → bronchi B alveoli → bronchiole → bronchi → trachea C trachea → alveoli →…

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May–June 2023, Paper 12

Question 21 · 1 mark

What are features of gas exchange surfaces in animals? A thick-walled and large surface area B thick-walled and small surface area C thin-walled and small surface area D…

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Question 23 · 1 mark

The diagram represents the exchange of gases during breathing and during respiration in the body, with oxygen and carbon dioxide moving between structure X (with blood) and…

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May–June 2023, Paper 13

Question 21 · 1 mark

In some animals, gas exchange occurs through the skin. What are the most likely characteristics of the skin in these animals? Columns: surface area; skin; blood supply. A large;…

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Question 22 · 1 mark

The diagram shows an alveolus and part of a blood vessel, with three arrows (1, 2 and 3) showing the direction of movement of gases. Which arrows represent oxygen only and carbon…

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May–June 2023, Paper 21

Question 20 · 1 mark

During inspiration, the processes listed take place. P volume of the thorax increases Q air rushes into the lungs R pressure in the thorax decreases S external intercostal muscles…

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May–June 2023, Paper 22

Question 20 · 1 mark

Different stages in the process of expiration are listed. 1 Rib cage moves downwards and inwards. 2 Volume of thorax decreases and pressure in lungs increases. 3 Air is pushed out…

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May–June 2023, Paper 23

Question 20 · 1 mark

What happens when a person breathes in? A The external intercostal muscles and the internal intercostal muscles contract. B The external intercostal muscles and the internal…

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May–June 2023, Paper 41

Question 3 · 14 marks

Fig. 3.1 is a photomicrograph of some cells lining the trachea, including a goblet cell and a cell labelled X. Describe the role of goblet cells.

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October–November 2023, Paper 11

Question 21 · 1 mark

Which table correctly shows the difference in composition of inspired air compared with expired air? Each option A–D is a table with rows oxygen and carbon dioxide and columns…

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Question 22 · 1 mark

What is the site of gas exchange in humans? A nose B alveoli C bronchus D trachea

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October–November 2023, Paper 12

Question 21 · 1 mark

What is the composition of expired air compared with inspired air? Columns: carbon dioxide; oxygen; water vapour. A decreased; increased; increased B decreased; decreased;…

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Question 22 · 1 mark

The diagram shows the human breathing system with three structures labelled 1, 2 and 3. What are the labelled structures? Columns: 1; 2; 3. A bronchus; bronchiole; trachea B…

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October–November 2023, Paper 13

Question 21 · 1 mark

Which row shows the composition of expired air from a healthy person? Columns: carbon dioxide %; oxygen %; water vapour. A 0.04; 21; saturated B 0.04; 16; variable C 4; 21;…

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Question 22 · 1 mark

What is the path of carbon dioxide as it leaves the lungs? A alveolus → bronchiole → bronchus → trachea B alveolus → bronchus → bronchiole → trachea C trachea → bronchiole →…

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October–November 2023, Paper 21

Question 21 · 1 mark

Which table correctly shows the difference in composition of inspired air compared with expired air? Each option A–D is a table with rows oxygen and carbon dioxide and columns…

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Question 22 · 1 mark

Which row shows the correct combination of muscle contractions and the pressure in the thorax when breathing out? Columns: internal intercostal muscles; external intercostal…

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October–November 2023, Paper 22

Question 21 · 1 mark

What is the composition of expired air compared with inspired air? Columns: carbon dioxide; oxygen; water vapour. A decreased; increased; increased B decreased; decreased;…

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Question 22 · 1 mark

During exercise, receptors detect a change in the blood and cause the breathing rate to increase. Which change do the receptors detect and where are they found in the body?…

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October–November 2023, Paper 23

Question 21 · 1 mark

Which row shows the composition of expired air from a healthy person? Columns: carbon dioxide %; oxygen %; water vapour. A 0.04; 21; saturated B 0.04; 16; variable C 4; 21;…

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October–November 2023, Paper 33

Question 4 · 12 marks

During inspiration air is taken into the lungs. Table 4.1 shows the structures that air passes through during inspiration (not in the correct order): A alveoli, B bronchi, C…

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October–November 2023, Paper 43

Question 3 · 16 marks

Complete Table 3.1 by writing in the percentages of carbon dioxide and oxygen in inspired air and in expired air.

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