IGCSE Biology (0610) — May–June 2023, Paper 21

40 questions · every question answerable online with instant point-by-point AI marking against the official mark scheme.

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Question 1 · 1 mark · Characteristics and classification of living organisms

What are characteristics of all organisms? A egestion and excretion B egestion and nutrition C excretion and nutrition D excretion and photosynthesis

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Question 2 · 1 mark · Characteristics and classification of living organisms

The scientific name for the golden eagle is Aquila chrysaetos. What is the genus of the golden eagle? A Aquila B chrysaetos C eagle D golden

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Question 3 · 1 mark · Cells

Which row shows structures that are present in both root hair cells and palisade mesophyll cells? Columns: cell wall, chloroplasts, cytoplasm, vacuole (key: ✓ = present, blank =…

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Question 4 · 1 mark · Cells

The photomicrograph shows a plant cell. The length of line XY is 90 mm. The actual length of the cell is 30 µm. What is the magnification of the photomicrograph? A ×300 B ×3000 C…

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Question 5 · 1 mark · Movement into and out of cells

The diagram shows an experiment demonstrating osmosis using a dialysis tubing bag containing sugar solution, connected to a glass tube and placed in water. After 30 minutes, the…

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Question 6 · 1 mark · Movement into and out of cells

The diagram shows the movement of glucose molecules across a cell membrane from a low concentration to a high concentration, using energy and a membrane molecule T. Which…

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Question 7 · 1 mark · Biological molecules

The diagram shows part of a protein molecule with one repeating sub-unit labelled X. What does X represent? A amino acid B fatty acid C glycerol D sugar

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Question 8 · 1 mark · Inheritance

The structure of DNA involves two strands coiled together to form a double helix. Which pairing of bases between the two strands is correct? A A and G B A and T C C and A D C and T

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Question 9 · 1 mark · Enzymes

What is true of all enzymes? Columns: they are sugars; they are most effective at pH 7 (key: ✓ = yes, blank = no). Which row A–D is correct? A B C D

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Question 10 · 1 mark · Enzymes

Which statement about human enzymes is correct when they are at temperatures above 80 °C? A The enzyme molecules are denatured. B The shape of the active site is stable. C More…

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Question 11 · 1 mark · Plant nutrition

An experiment is set up to investigate gas exchange in aquatic plants. An aquatic plant is placed in hydrogencarbonate indicator solution in the light. The hydrogencarbonate…

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Question 12 · 1 mark · Plant nutrition

Certain factors are needed for photosynthesis. If a factor is in short supply, it limits the rate of photosynthesis. Which of these could be limiting factors? 1 carbon dioxide 2…

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Question 13 · 1 mark · Human nutrition

The haemoglobin concentration in the blood of a person is 80 g / dm³. The accepted normal concentration is 120 g / dm³ or above. Which substance may be lacking in their diet? A…

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Question 14 · 1 mark · Human nutrition

Which statement about physical digestion is correct? A It increases the surface area of food. B It involves enzymes. C It takes place in the mouth only. D It produces smaller…

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Question 15 · 1 mark · Transport in plants

Which statement describes the effect of atmospheric humidity on the rate of transpiration? A In high humidity, the transpiration rate is high because there is slow diffusion of…

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Question 16 · 1 mark · Transport in plants

Sucrose and amino acids move around a plant from sources to sinks. Which row shows the sources and sinks? Columns: root cortex cells; xylem vessels; palisade mesophyll cells. A…

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Question 17 · 1 mark · Transport in animals

Which statements describe how the structures in the circulatory system function? 1 a muscular pump to push blood into vessels 2 valves to ensure one-way blood flow 3 veins to take…

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Question 18 · 1 mark · Transport in animals

The diagram shows a section through the heart with four parts labelled A, B, C and D. Which part is the septum? A B C D

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Question 19 · 1 mark · Diseases and immunity

The cholera bacterium toxin causes dehydration and loss of salts from the blood in humans. Which statement explains the reason for this? A Chloride ions are secreted into the…

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Question 20 · 1 mark · Gas exchange in humans

During inspiration, the processes listed take place. P volume of the thorax increases Q air rushes into the lungs R pressure in the thorax decreases S external intercostal muscles…

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Question 21 · 1 mark · Respiration

In the chemical equation for anaerobic respiration in yeast, the numbers have been replaced by the letters W, X, Y and Z: C(W)H(X)O(W) → Y·C(Y)H(Z)OH + Y·CO(Y). Which number is Z?…

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Question 22 · 1 mark · Respiration

A student measured their oxygen consumption before, during and after exercise. The results are shown in the graph (oxygen consumption / dm³ per minute against time / minutes, with…

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Question 23 · 1 mark · Excretion in humans

Which row shows where glucose will be found in the body of a healthy human after eating a meal? Columns: renal artery; renal vein; glomerulus; nephron; ureter (yes/no). A yes; no;…

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Question 24 · 1 mark · Coordination and response

The events listed involve neurotransmitter molecules at a synapse. 1 They bind with receptor proteins. 2 They diffuse across the synaptic gap. 3 They enter the synaptic gap. 4…

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Question 25 · 1 mark · Coordination and response

What occurs during accommodation to focus on distant objects? Columns: ciliary muscle; lens shape; suspensory ligaments. A contracts; fat; slack B relaxes; thin; tight C…

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Question 26 · 1 mark · Coordination and response

What is a correct statement about auxin in shoots? A It is made only on the shaded side of the shoot. B It is more concentrated on the side of the shoot that receives the most…

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Question 27 · 1 mark · Variation and selection

What is a correct statement about antibiotics? A Bacteria may become resistant to antibiotics as a result of artificial selection. B Bacteria may become resistant to antibiotics…

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Question 28 · 1 mark · Cell division

Potatoes are stem tubers. A tuber can be placed in the ground to grow into another plant, which can grow many more tubers (asexual reproduction shown over 4 months). The diploid…

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Question 29 · 1 mark · Reproduction

Which row about asexual reproduction is correct? Columns: number of parents; offspring identical to parents; offspring identical to each other. A one; no; yes B one; yes; yes C…

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Question 30 · 1 mark · Inheritance

The statements describe how a protein is made. 1 mRNA passes through a ribosome. 2 mRNA molecules carry a copy of the gene to the cytoplasm. 3 The gene coding for the protein is…

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Question 31 · 1 mark · Inheritance

Which parents could produce offspring with blood group O? A heterozygous father with blood group A and heterozygous mother with blood group B B heterozygous father with blood…

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Question 32 · 1 mark · Inheritance

The diagram shows the inheritance of albinism in one family. Albinism is an inherited condition caused by a recessive allele. The pedigree shows generations with unaffected…

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Question 33 · 1 mark · Variation and selection

Which term is a genetic change? A allele B genotype C mutation D phenotype

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Question 34 · 1 mark · Organisms and their environment

Which adaptation may be present in a xerophyte? A leaves with small surface area and large numbers of stomata B little or no xylem tissue and leaves with large surface area C…

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Question 35 · 1 mark · Organisms and their environment

The diagram shows energy flow from the Sun, through a food chain (plant → animal → animal) and into the environment, with arrow 1 from the Sun to the plant and arrow 2 along the…

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Question 36 · 1 mark · Organisms and their environment

A few yeast cells were placed in a container of nutrient solution. The graph shows how their population size changed over time, with four numbered phases (1 lag, 2 exponential, 3…

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Question 37 · 1 mark · Human influences on ecosystems

The number of Atlantic bluefin tuna fish found in the Atlantic Ocean has significantly decreased in the last 50 years. Which method would make the biggest improvement in the…

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Question 38 · 1 mark · Human influences on ecosystems

The bloodworm is an organism that is found in heavily polluted water. The diagram shows where raw sewage flows into a river, with four sampling points A, B, C and D along the…

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Question 39 · 1 mark · Biotechnology and genetic modification

The diagram shows a bacterial cell with four parts labelled A, B, C and D. Which part is useful in genetic modification? A B C D

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Question 40 · 1 mark · Variation and selection

Which statement about genetic modification is correct? A It involves choosing which individual organisms are used for breeding. B It is always done using genes from the same…

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