AS & A Level Biology (9700) — February–March 2023, Paper 12

40 questions · every question answerable online with instant point-by-point AI marking against the official mark scheme.

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Question 1 · 1 mark

The photomicrograph shows cells from a human blood smear, labelled with a line PQ across a neutrophil and a cell Q. Which calculation shows a correct method to calculate the…

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Question 2 · 1 mark

A student calibrated an eyepiece graticule using a stage micrometer. - Each division of the stage micrometer was 0.01 mm. - With a ×10 magnification objective lens, 10 eyepiece…

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Question 3 · 1 mark

Which statements are correct for chloroplasts and also for mitochondria? 1 They contain 80S ribosomes. 2 They can transcribe their circular DNA. 3 They can translate mRNA. 4 They…

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Question 4 · 1 mark

The electron micrograph shows some cells from a root, with four structures labelled A, B, C and D. Which cell structure is not usually found in cells from a root?

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Question 5 · 1 mark

Dialysis (Visking) tubing is an artificial partially permeable membrane with pore sizes of approximately 2.5 nm. Glucose molecules have a diameter of about 1.5 nm and can pass…

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Question 6 · 1 mark

What is present in all viruses? A ribose B deoxyribose C adenine D thymine

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Question 7 · 1 mark

To estimate the concentration of glucose in an unknown solution, equal volumes of a range of known concentrations of glucose were each mixed with the same excess volume of…

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Question 8 · 1 mark

Which statements are correct for amylose and also for amylopectin? 1 They are carbohydrate molecules. 2 They are formed by condensation reactions. 3 They are linear molecules. 4…

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Question 9 · 1 mark

Which statement is a correct comparison between saturated triglyceride molecules and unsaturated triglyceride molecules of approximately the same molecular masses? A Unsaturated…

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Question 10 · 1 mark

The diagram represents a molecule from a cell surface membrane, with four parts labelled A, B, C and D. Which description of one of the labels is correct? A fatty acid at the…

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Question 11 · 1 mark

Which row correctly shows levels of protein structure that can be held together by each type of interaction (hydrogen bonds, covalent bonds, hydrophobic interactions)? A hydrogen…

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Question 12 · 1 mark

Which molecules contain at least three double bonds? Four molecules are shown: a saturated triglyceride (A or C area), collagen, haemoglobin and one further labelled molecule,…

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Question 13 · 1 mark

Which diagram correctly shows hydrogen bonding between two water molecules? Four diagrams A, B, C and D each show two water molecules with partial or full charges marked; the…

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Question 14 · 1 mark

Which statement describes an example of an extracellular enzyme? A Amylase in saliva is an enzyme that catalyses the breakdown of starch in the mouth. B Carbonic anhydrase is an…

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Question 15 · 1 mark

Which row is correct for enzymes that catalyse reactions using the lock-and-key hypothesis (effect on activation energy; shape of active site compared to the substrate)? A lowers…

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Question 16 · 1 mark

A scientist investigated the rate of breakdown of hydrogen peroxide. Four experiments were carried out using different mixtures: substrate only; substrate + enzyme; substrate +…

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Question 17 · 1 mark

Which of these substances can pass directly through cell surface membranes without using a carrier protein or a channel protein? 1 Ca²⁺ 2 CO₂ 3 C₆H₁₂O₆ A 1 and 2 B 1 and 3 C 2 and…

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Question 18 · 1 mark

What happens to the surface area to volume ratio of a cube when the length of each side is doubled? A The ratio decreases by four times. B The ratio halves. C The ratio doubles. D…

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Question 19 · 1 mark

Which events are part of the mitotic cell cycle? 1 interphase 2 telophase 3 cytokinesis A 1, 2 and 3 B 1 and 2 only C 1 and 3 only D 2 and 3 only

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Question 20 · 1 mark

The estimated total number of red blood cells in the human body is 2.5 × 10¹³. It is estimated that, each day, 2.5 × 10¹¹ red blood cells are removed from the circulation and are…

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Question 21 · 1 mark

DNA polymerase catalyses condensation reactions between molecules during semi-conservative replication of DNA. What is joined by DNA polymerase? A base and base B base and…

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Question 22 · 1 mark

Two polynucleotide strands make up a DNA molecule. Which description is correct? A The percentage of cytosine is 50% of that of guanine in the whole molecule. B The percentage of…

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Question 23 · 1 mark

The PDx1 protein is found in a wide range of animal species where it is regarded as essential for normal metabolism. In sand rats, the PDx1 gene coding for the PDx1 protein has a…

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Question 24 · 1 mark

Different tissues in a plant were supplied with a radioactively labelled substance to identify which tissues were actively synthesising mRNA. Which radioactively labelled…

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Question 25 · 1 mark

Which row correctly matches the structure and function of phloem sieve tube elements? A structure: peripheral cytoplasm with no nucleus; function: to provide as little resistance…

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Question 26 · 1 mark

Which feature of xylem vessel elements helps adhesion during transpiration? A Lignin forms a complete secondary wall. B New vessels carry extra water as the plants grow. C There…

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Question 27 · 1 mark

Mass flow is the bulk movement of materials from one place to another. How many of the vessels listed carry fluids by mass flow? - artery - phloem sieve tube - vein - xylem vessel…

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Question 28 · 1 mark

Cellulose, lignin and suberin are components of various plant cell walls. Descriptions of these cell wall components are listed. 1 a component of the Casparian strip 2 redirects…

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Question 29 · 1 mark

The arrows show the direction of water movement across a plant root, from water in the soil to the xylem. Arrows are numbered 1 to 8, with plasmodesmata marked at certain points.…

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Question 30 · 1 mark

Which row correctly identifies sources and sinks of sugars (root cells absorbing mineral ions; storage cells of a seed that is starting to grow)? A root cells: sink; storage…

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Question 31 · 1 mark

The photomicrograph shows a section through a tissue with an artery. Which row correctly shows the type of artery and whether the blood inside the artery is oxygenated or…

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Question 32 · 1 mark

Heart surgery may cause a decrease in the transmission of impulses in the Purkyne tissue to the right side of the heart. What is a possible effect of this decrease? A Impulses…

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Question 33 · 1 mark

The diagram shows a network of blood vessels that supply blood to muscle tissue in the human body, with an artery feeding capillaries and a vein draining them. Point X is in the…

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Question 34 · 1 mark

Scientists have shown that the oxygen dissociation curves for haemoglobin of smaller mammals are to the right of those of larger mammals. What does this suggest about the…

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Question 35 · 1 mark

What is an effect of an increased concentration of carbon dioxide in the blood? A increased movement of chloride ions out of red blood cells B increased concentration of…

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Question 36 · 1 mark

Two of the requirements of an efficient gas exchange system are a large surface area and a short diffusion distance. Which row correctly describes how alveoli are adapted to meet…

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Question 37 · 1 mark

What defines infectious diseases? A Symptoms are caused by a bacterium that passes from contaminated air, soil or water to a host. B Symptoms are caused by a pathogen that is…

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Question 38 · 1 mark

A hurricane destroys a large town on an island. People move away from the town and set up tents, where sanitation is poor. Which disease is most likely to spread within a week of…

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Question 39 · 1 mark

Which statement correctly explains why viruses are unaffected by penicillin? A Penicillin only affects host cell metabolism. B Penicillin only binds with 70S ribosomes. C…

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Question 40 · 1 mark

Which processes characterise the mode of action of phagocytes? 1 antibody production 2 receptor binding 3 endocytosis 4 exocytosis 5 hydrolysis A 1, 2 and 4 B 1 and 4 only C 2, 3,…

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